Jacob is back in the hospital for the second time this month. I brought him in a couple of weeks ago because he was spiking a fever and for a BMT patient, that can be very serious. After a couple of days, Jacob seemed to be improving and there were no red flags in his work ups, so he was able to come home. He came back positive for a virus, but the doctor thought his body would be able to fight it off over time. Jacob really did seem to be doing better for the past week. We went in for his check up on Friday and his liver function tests were way off, however. The doctor thought it might’ve been from the virus, but wasn’t sure. He had planned on retesting him today or tomorrow, but Jacob was spiking a fever this morning and had thrown up a couple of times, so the doctor had us bring him back in to the hospital right away. Jacob is sleeping now and getting some iv hydration, along with some antibiotics. He took some Tylenol an hour and a half ago, but his fever has stayed the same. The doctors are considering moving him over to PICU so he can be more closely monitored.
We also recently found out that Jacob’s new bone marrow is almost entirely gone. His body rejected the graft and he has mostly his old cells back now. A lot of people ask where we go from here. The doctors have talked about infusing more cells from the same donor. This idea may have worked a couple months ago when he still had more donor cells, but now it is pretty much just a shot in the dark. Another option could be to do a second BMT. The thought of putting Jacob through that and starting all over again turns my stomach. He is still so fragile and weak from the first time around and from whatever he is fighting now, it just seems like a bad idea. I’m not even certain that his body could handle it. He definitely couldn’t handle it in the condition that he is in right now. I told the doctors we are not ready for that. For now, we just hope that his body heals and that his prophylactic medications protect him from CGD related infections.